8FI5

Crystal Structure of Glycylpeptide N-tetradecanoyltransferase (N-myristoyl transferase) (NMT) from Leishmania major Friedlin bound to tetradecanoyl-CoA (Orthorhombic P Form 2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Glycylpeptide N-tetradecanoyltransferase	polymer	425	49174.9	1	UniProt (A0A8J9XEH4) Pfam (PF01233) Pfam (PF02799) UniProt (by SIFTS) (Q4Q5S8) In PDB	Leishmania major strain Friedlin
2	A	TETRADECANOYL-COA	non-polymer		977.9	1	Chemie (MYA)
3		water	water		18.0	96	Chemie (HOH)

Sequence modifications

A: 6 - 421 (UniProt: A0A8J9XEH4)

PDB	External Database	Details
Met -3	-	initiating methionine
Ala -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
Met 5	-	expression tag
Arg 148	Lys 148	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	49174.9
Non-Polymers*	Number of molecules	1
	Total formula weight	977.9
All*	Total formula weight	50152.8

*Water molecules are not included.