8FHU

Structure of Pyruvate dehydrogenase phosphatase regulatory subunit epitope presented by H2-Dd

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	H-2 class I histocompatibility antigen, D-D alpha chain	polymer	277	32265.9	2	UniProt (P01900) Pfam (PF00129) Pfam (PF07654) In PDB	Mus musculus (house mouse)	H-2D(D)
2	B, E	Beta-2-microglobulin	polymer	99	11704.4	2	UniProt (P01887) Pfam (PF07654) In PDB	Mus musculus (house mouse)
3	C, F	Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial	polymer	9	940.1	2	UniProt (Q8NCN5) In PDB	Homo sapiens	PDPr
4	A, D	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
5		water	water		18.0	184	Chemie (HOH)

Sequence modifications

A, D: 2 - 277 (UniProt: P01900)

PDB	External Database	Details
Met 1	-	initiating methionine

B, E: 1 - 99 (UniProt: P01887)

PDB	External Database	Details
Asp 85	Ala 105	variant

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	89820.8
Non-Polymers*	Number of molecules	2
	Total formula weight	78.2
All*	Total formula weight	89899.0

*Water molecules are not included.