8FH3
Human IFT-A complex structures provide molecular insights into ciliary transport
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | WD repeat-containing protein 35 | polymer | 1181 | 133705.6 | 1 | UniProt (Q9P2L0) Pfam (PF24797) Pfam (PF23390) Pfam (PF23387) Pfam (PF25170) Pfam (PF25768) Pfam (PF23145) | Homo sapiens (human) | Intraflagellar transport protein 121 homolog |
| 2 | B (B) | Intraflagellar transport protein 122 homolog | polymer | 1241 | 141993.7 | 1 | UniProt (Q9HBG6) Pfam (PF25144) Pfam (PF25143) Pfam (PF23381) Pfam (PF23377) Pfam (PF25295) | Homo sapiens (human) | WD repeat-containing protein 10,WD repeat-containing protein 140 |
| 3 | C (C) | WD repeat-containing protein 19 | polymer | 1342 | 151760.4 | 1 | UniProt (Q8NEZ3) Pfam (PF23389) Pfam (PF15911) Pfam (PF24762) Pfam (PF23146) Pfam (PF23145) | Homo sapiens (human) | Intraflagellar transport 144 homolog |
| 4 | D (E) | Intraflagellar transport protein 140 homolog | polymer | 1462 | 165404.3 | 1 | UniProt (Q96RY7) Pfam (PF23383) Pfam (PF23385) Pfam (PF24762) Pfam (PF24760) | Homo sapiens (human) | WD and tetratricopeptide repeats protein 2 |
| 5 | E (I) | Tubby-related protein 3 | polymer | 442 | 49710.1 | 1 | UniProt (O75386) Pfam (PF16322) Pfam (PF01167) | Homo sapiens (human) | Tubby-like protein 3 |
| 6 | F, G, H, I (B, C) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
B: 1 - 1241 (UniProt: Q9HBG6)
| PDB | External Database | Details |
|---|---|---|
| Asp 227 | Glu 238 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 642574.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 642835.7 |
