8FH1
Crystal structure of mutant Androgen Receptor ligand binding domain F877L/T878A with DHT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 258 | 30030.1 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (human) | Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
| 2 | B (A) | 5-ALPHA-DIHYDROTESTOSTERONE | non-polymer | 290.4 | 1 | Chemie (DHT) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
A: 663 - 920 (UniProt: P10275)
| PDB | External Database | Details |
|---|---|---|
| Leu 877 | Phe 877 | engineered mutation |
| Ala 878 | Thr 878 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30030.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 386.5 | |
| All* | Total formula weight | 30416.6 |
