8FGB
Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)-6-methylpyrimidin-2-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nitric oxide synthase, brain | polymer | 422 | 48812.5 | 2 | UniProt (P29476) Pfam (PF02898) | Rattus norvegicus (Norway rat) | BNOS,Constitutive NOS,NC-NOS,NOS type I,Neuronal NOS,nNOS,Peptidyl-cysteine S-nitrosylase NOS1 |
| 2 | C, G (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, H (A, B) | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 2 | Chemie (H4B) | |||
| 4 | E, I (A, B) | 4-(2-{5-[2-(dimethylamino)ethyl]-2,3-difluorophenyl}ethyl)-6-methylpyrimidin-2-amine | non-polymer | 320.4 | 2 | Chemie (V80) | |||
| 5 | F, J (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 6 | K (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 308 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97625.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2539.7 | |
| All* | Total formula weight | 100164.8 |
