8FEZ
Prefusion-stabilized SARS-CoV-2 spike protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1243 | 137991.8 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
Sequence modifications
A, B, C: 1 - 1208 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 682 | Arg 682 | conflict |
| Ser 683 | Arg 683 | conflict |
| Ser 685 | Arg 685 | conflict |
| Leu 856 | Asn 856 | engineered mutation |
| Gln 899 | Ala 899 | engineered mutation |
| Phe 916 | Leu 916 | engineered mutation |
| Trp 917 | Tyr 917 | engineered mutation |
| Asp 941 | Thr 941 | engineered mutation |
| Leu 956 | Ala 956 | engineered mutation |
| Glu 964 | Lys 964 | engineered mutation |
| Asn 985 | Asp 985 | engineered mutation |
| Pro 986 | Lys 986 | conflict |
| Pro 987 | Val 987 | conflict |
| Gln 1143 | Pro 1143 | engineered mutation |
| Gly 1209 | - | expression tag |
| Ser 1210 | - | expression tag |
| Gly 1211 | - | expression tag |
| Tyr 1212 | - | expression tag |
| Ile 1213 | - | expression tag |
| Pro 1214 | - | expression tag |
| Glu 1215 | - | expression tag |
| Ala 1216 | - | expression tag |
| Pro 1217 | - | expression tag |
| Arg 1218 | - | expression tag |
| Asp 1219 | - | expression tag |
| Gly 1220 | - | expression tag |
| Gln 1221 | - | expression tag |
| Ala 1222 | - | expression tag |
| Tyr 1223 | - | expression tag |
| Val 1224 | - | expression tag |
| Arg 1225 | - | expression tag |
| Lys 1226 | - | expression tag |
| Asp 1227 | - | expression tag |
| Gly 1228 | - | expression tag |
| Glu 1229 | - | expression tag |
| Trp 1230 | - | expression tag |
| Val 1231 | - | expression tag |
| Leu 1232 | - | expression tag |
| Leu 1233 | - | expression tag |
| Ser 1234 | - | expression tag |
| Thr 1235 | - | expression tag |
| Phe 1236 | - | expression tag |
| Leu 1237 | - | expression tag |
| His 1238 | - | expression tag |
| His 1239 | - | expression tag |
| His 1240 | - | expression tag |
| His 1241 | - | expression tag |
| His 1242 | - | expression tag |
| His 1243 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 413975.4 | |
| All* | Total formula weight | 413975.4 |
