8FE2
Structure of J-PKAc chimera complexed with Aplithianine A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha | polymer | 405 | 47591.9 | 2 | UniProt (P25685) UniProt (P17612) Pfam (PF00226) Pfam (PF00069) In PDB | Homo sapiens (human) | DnaJ protein homolog 1, Heat shock protein 40 |
2 | I, J | cAMP-dependent protein kinase inhibitor alpha | polymer | 20 | 2226.4 | 2 | UniProt (P61925) In PDB | Homo sapiens | PKI-alpha,cAMP-dependent protein kinase inhibitor,muscle/brain isoform |
3 | A, B | 6-[(6M)-6-(1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-9H-purine | non-polymer | 299.4 | 2 | Chemie (XTI) | |||
4 | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 99636.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 598.7 | |
All* | Total formula weight | 100235.4 |