8FCT
Cryo-EM structure of p97:UBXD1 lariat mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (F, A, B, C, D...) | Transitional endoplasmic reticulum ATPase | polymer | 806 | 89436.8 | 6 | UniProt (P55072) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862) | Homo sapiens (human) | TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP |
| 2 | G (G) | UBX domain-containing protein 6 | polymer | 441 | 49823.7 | 1 | UniProt (Q9BZV1) Pfam (PF09409) Pfam (PF00789) | Homo sapiens (human) | UBX domain-containing protein 1 |
| 3 | H, I, J, K, L... (F, A, B, C, D...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 12 | Chemie (ADP) |
Sequence modifications
G: 1 - 441 (UniProt: Q9BZV1)
| PDB | External Database | Details |
|---|---|---|
| Arg 299 | Glu 299 | engineered mutation |
| Glu 302 | Arg 302 | engineered mutation |
| Glu 307 | Arg 307 | engineered mutation |
| Arg 312 | Glu 312 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 586444.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 5126.4 | |
| All* | Total formula weight | 591571.0 |
