8FCD
HIV-1 Reverse Transcriptase in complex with 6-membered bicyclic core NNRTI
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | p66 RT | polymer | 560 | 64562.9 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) | HIV whole-genome vector AA1305#18 | Reverse transcriptase/ribonuclease H,Exoribonuclease H,p66 RT |
| 2 | B (B) | p51 RT | polymer | 440 | 51399.0 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) | HIV whole-genome vector AA1305#18 | |
| 3 | C (A) | 4-[(8-{4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino]benzonitrile | non-polymer | 421.5 | 1 | Chemie (ZJ2) | |||
| 4 | D (A) | L(+)-TARTARIC ACID | non-polymer | 150.1 | 1 | Chemie (TLA) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115962.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 571.5 | |
| All* | Total formula weight | 116533.5 |
