8FAC

Structure of the leucine-rich repeat kinase 1 monomer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Leucine-rich repeat serine/threonine-protein kinase 1	polymer	2048	229556.4	1	UniProt (Q38SD2) Pfam (PF00560) Pfam (PF08477) Pfam (PF16095) Pfam (PF00069) In PDB	Homo sapiens (human)
2	A	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)

Sequence modifications

A: 1 - 2015 (UniProt: Q38SD2)

PDB	External Database	Details
Met -32	-	initiating methionine
Asp -31	-	expression tag
Tyr -30	-	expression tag
Lys -29	-	expression tag
Asp -28	-	expression tag
His -27	-	expression tag
Asp -26	-	expression tag
Gly -25	-	expression tag
Asp -24	-	expression tag
Tyr -23	-	expression tag
Lys -22	-	expression tag
Asp -21	-	expression tag
His -20	-	expression tag
Asp -19	-	expression tag
Ile -18	-	expression tag
Asp -17	-	expression tag
Tyr -16	-	expression tag
Lys -15	-	expression tag
Asp -14	-	expression tag
Asp -13	-	expression tag
Asp -12	-	expression tag
Asp -11	-	expression tag
Lys -10	-	expression tag
Leu -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Glu -6	-	expression tag
Val -5	-	expression tag
Leu -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Pro 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	229556.4
Non-Polymers*	Number of molecules	1
	Total formula weight	443.2
All*	Total formula weight	229999.6

*Water molecules are not included.