8FAB
CRYSTAL STRUCTURE OF THE FAB FRAGMENT FROM THE HUMAN MYELOMA IMMUNOGLOBULIN IGG HIL AT 1.8 ANGSTROMS RESOLUTION
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | IGG1-LAMBDA HIL FAB (LIGHT CHAIN) | polymer | 212 | 22767.2 | 2 | PIR (S25738) | Homo sapiens (human) | |
| 2 | B, D | IGG1-LAMBDA HIL FAB (HEAVY CHAIN) | polymer | 224 | 24090.2 | 2 | EMBL (Y14737) | Homo sapiens (human) | |
| 3 | water | water | 18.0 | 668 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 212 (PIR: S25738)
B, D: 2 - 224 (EMBL: Y14737)
| PDB | External Database | Details |
|---|---|---|
| Arg 19 | Ser 38 | CONFLICT |
| Ala 24 | Gly 43 | CONFLICT |
| Asn 25 | Asp 44 | CONFLICT |
| Ala 26 | Thr 45 | CONFLICT |
| Pro 28 | Gly 47 | CONFLICT |
| Asn 29 | Asp 48 | CONFLICT |
| Gln 30 | Lys 49 | CONFLICT |
| Tyr 33 | Cys 52 | CONFLICT |
| Arg 41 | His 60 | CONFLICT |
| Ala 42 | Ser 61 | CONFLICT |
| Met 45 | Leu 64 | CONFLICT |
| Tyr 48 | Phe 67 | CONFLICT |
| Lys 49 | Gln 68 | CONFLICT |
| Thr 51 | Ser 70 | CONFLICT |
| Gln 52 | Lys 71 | CONFLICT |
| Gln 59 | Glu 78 | CONFLICT |
| Ser 63 | Gly 82 | CONFLICT |
| Thr 65 | Asn 84 | CONFLICT |
| Thr 68 | Asn 87 | CONFLICT |
| Val 70 | Ala 89 | CONFLICT |
| Val 77 | Thr 96 | CONFLICT |
| Glu 80 | Met 99 | CONFLICT |
| Asn 92 | Ser 111 | CONFLICT |
| Ala 94 | Thr 113 | CONFLICT |
| Ser 95 | Ala 114 | CONFLICT |
| Ile 96 | Val 115 | CONFLICT |
| Ile 155 | Val 174 | CONFLICT |
| PDB | External Database | Details |
|---|---|---|
| Lys 3 | Gln 22 | CONFLICT |
| Gln 6 | Glu 25 | CONFLICT |
| Ala 7 | Ser 26 | CONFLICT |
| Ile 23 | Ala 42 | CONFLICT |
| Val 50 | Ala 69 | CONFLICT |
| Asn 54 | Asp 73 | CONFLICT |
| Arg 57 | Asn 76 | CONFLICT |
| Thr 58 | Lys 77 | CONFLICT |
| Gly 61 | Ala 80 | CONFLICT |
| Arg 77 | Asn 96 | CONFLICT |
| Thr 88 | Ala 107 | CONFLICT |
| - | Arg 117 | DELETION |
| - | Glu 118 | DELETION |
| - | Gly 119 | DELETION |
| - | Arg 120 | DELETION |
| - | Trp 121 | DELETION |
| - | Val 122 | DELETION |
| Asp 99 | Tyr 124 | CONFLICT |
| Pro 100 | Thr 125 | CONFLICT |
| Asp 101 | Thr 126 | CONFLICT |
| Ile 102 | Val 127 | CONFLICT |
| Leu 103 | Thr 128 | CONFLICT |
| - | Ile 130 | DELETION |
| Ala 105 | Gly 131 | CONFLICT |
| Phe 106 | Tyr 132 | CONFLICT |
| Ser 107 | Tyr 133 | CONFLICT |
| Val 115 | Thr 141 | CONFLICT |
| Lys 218 | Arg 244 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93714.8 | |
| All* | Total formula weight | 93714.8 |
