8F9Z
Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-14204, an HIV-1 gp120 antagonist
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HIV-1 gp120 core | polymer | 353 | 39160.4 | 1 | UniProt (A0A0M3KKW8) Pfam (PF00516) | Homo sapiens (human) | |
| 2 | B, C, D, E, F... (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 3 | H (A) | (5M)-N-{(1S)-2-amino-1-[5-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl}-5-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrole-2-carboxamide | non-polymer | 411.4 | 1 | Chemie (XKW) | |||
| 4 | I (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 5 | J (A) | water | water | 18.0 | 277 | Chemie (HOH) |
Sequence modifications
A: 44 - 492 (UniProt: A0A0M3KKW8)
| PDB | External Database | Details |
|---|---|---|
| Ser 375 | His 242 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39160.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1977.0 | |
| All* | Total formula weight | 41137.3 |
