8F9O

Dog sialic acid esterase (SIAE)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Sialic acid acetylesterase	polymer	496	56173.6	1	UniProt (A0A8C0LZX8) Pfam (PF03629)	Canis lupus familiaris (dog)
2	B (B)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1057.0	1	In PDB GlyTouCan (G82348BZ)
3	C (C)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
4	D (D)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
5	E (E)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	F (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
7	G (A)	water	water		18.0	850	Chemie (HOH)

Sequence modifications

A: 25 - 510 (UniProt: A0A8C0LZX8)

PDB	External Database	Details
Asp 15	-	expression tag
Arg 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
His 20	-	expression tag
His 21	-	expression tag
His 22	-	expression tag
Lys 23	-	expression tag
Leu 24	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	56173.6
Branched	Number of molecules	4
	Total formula weight	2816.6
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	59211.4

*Water molecules are not included.