8F97
Compound 5 bound to procaspase-6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Procaspase-6 | polymer | 299 | 34121.8 | 4 | UniProt (P55212) Pfam (PF00656) | Homo sapiens (human) | CASP-6,CSP-6,Apoptotic protease Mch-2 |
| 2 | E, J (A, C) | 2-({[(2M)-[2,3'-bipyridin]-2'-yl]amino}methyl)-5-fluorophenol | non-polymer | 295.3 | 2 | Chemie (XM6) | |||
| 3 | F, G, H, K, L... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 4 | I (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | O (D) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | P (D) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 435 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 293 (UniProt: P55212)
| PDB | External Database | Details |
|---|---|---|
| Ala 163 | Cys 163 | conflict |
| Glu 294 | - | expression tag |
| Asn 295 | - | expression tag |
| Leu 296 | - | expression tag |
| Tyr 297 | - | expression tag |
| Phe 298 | - | expression tag |
| Gln 299 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 136487.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1258.8 | |
| All* | Total formula weight | 137746.0 |
