8F96
Compound 3 bound to procaspase-6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Procaspase-6 | polymer | 299 | 34121.8 | 4 | UniProt (P55212) Pfam (PF00656) | Homo sapiens (human) | CASP-6,CSP-6,Apoptotic protease Mch-2 |
| 2 | E, F (B, C) | 5-fluoro-2-({[(3M)-3-(pyrimidin-4-yl)pyridin-2-yl]amino}methyl)phenol | non-polymer | 296.3 | 2 | Chemie (XLW) | |||
| 3 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 293 (UniProt: P55212)
| PDB | External Database | Details |
|---|---|---|
| Ala 163 | Cys 163 | conflict |
| Glu 294 | - | expression tag |
| Asn 295 | - | expression tag |
| Leu 296 | - | expression tag |
| Tyr 297 | - | expression tag |
| Phe 298 | - | expression tag |
| Gln 299 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 136487.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 592.6 | |
| All* | Total formula weight | 137079.8 |
