8F8K

The structure of Rv2173 from M. tuberculosis with IPP bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	(2E,6E)-farnesyl diphosphate synthase	polymer	387	41981.6	1	UniProt (O53507) Pfam (PF00348)	Mycobacterium tuberculosis
2	B, H (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
3	C, D, E, G (A)	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
4	F (A)	3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE	non-polymer		246.1	1	Chemie (IPE)
5	I, J, K (A)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
6	L (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
7	M (A)	water	water		18.0	92	Chemie (HOH)

Sequence modifications

A: 1 - 352 (UniProt: O53507)

PDB	External Database	Details
Met -34	-	expression tag
Ser -33	-	expression tag
Tyr -32	-	expression tag
Tyr -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
Leu -24	-	expression tag
Glu -23	-	expression tag
Ser -22	-	expression tag
Thr -21	-	expression tag
Ser -20	-	expression tag
Leu -19	-	expression tag
Tyr -18	-	expression tag
Lys -17	-	expression tag
Lys -16	-	expression tag
Ala -15	-	expression tag
Gly -14	-	expression tag
Ser -13	-	expression tag
Ala -12	-	expression tag
Ala -11	-	expression tag
Ala -10	-	expression tag
Leu -9	-	expression tag
Phe -8	-	expression tag
Arg -7	-	expression tag
Phe -6	-	expression tag
Lys -5	-	expression tag
Lys -4	-	expression tag
Glu -3	-	expression tag
Pro -2	-	expression tag
Phe -1	-	expression tag
Thr 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41981.6
Non-Polymers*	Number of molecules	11
	Total formula weight	822.1
All*	Total formula weight	42803.8

*Water molecules are not included.