8F7X
Gi bound nociceptin receptor in complex with nociceptin peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | R | Nociceptin receptor | polymer | 369 | 40597.9 | 1 | UniProt (P41146) Pfam (PF00001) In PDB | Homo sapiens (human) | Kappa-type 3 opioid receptor,KOR-3,Orphanin FQ receptor |
2 | P | Nociceptin | polymer | 14 | 1499.8 | 1 | UniProt (Q13519) In PDB | Homo sapiens | Orphanin FQ,PPNOC |
3 | A | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40445.1 | 1 | UniProt (P63096) Pfam (PF00503) In PDB | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
4 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 353 | 39020.7 | 1 | UniProt (P54311) Pfam (PF00400) In PDB | Rattus norvegicus (Norway rat) | Transducin beta chain 1 |
5 | C | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 68 | 7563.8 | 1 | UniProt (P63212) Pfam (PF00631) In PDB | Bos taurus (cattle) | G gamma-I |
6 | E | scFv16 | polymer | 248 | 26408.5 | 1 | synthetic construct |
Sequence modifications
A: 1 - 354 (UniProt: P63096)
B: 2 - 340 (UniProt: P54311)
PDB | External Database | Details |
---|---|---|
Ala 203 | Gly 203 | conflict |
Ser 326 | Ala 326 | conflict |
PDB | External Database | Details |
---|---|---|
Met -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Leu -1 | - | expression tag |
Leu 0 | - | expression tag |
Gln 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 155535.6 | |
All* | Total formula weight | 155535.6 |