8F7U
Macrocyclic Plasmin Inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Activation peptide | polymer | 250 | 27319.4 | 2 | UniProt (P00747) Pfam (PF00089) In PDB | Homo sapiens (human) | |
2 | A, B | (5S,8R,18S,21R)-N-{[4-(aminomethyl)phenyl]methyl}-21-[(benzenesulfonyl)amino]-3,11,20-trioxo-2,5,8,12,19-pentaazatetracyclo[21.2.2.2~5,8~.2~13,16~]hentriaconta-1(25),13,15,23,26,28-hexaene-18-carboxamide | non-polymer | 780.9 | 2 | Chemie (GGI) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 465 | Chemie (HOH) |
Sequence modifications
A, B: 542 - 791 (UniProt: P00747)
PDB | External Database | Details |
---|---|---|
Ala 741 | Ser 760 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 54638.8 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 2230.3 | |
All* | Total formula weight | 56869.1 |