8F7U
Macrocyclic Plasmin Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Activation peptide | polymer | 250 | 27319.4 | 2 | UniProt (P00747) Pfam (PF00089) | Homo sapiens (human) | |
| 2 | C, F (A, B) | (5S,8R,18S,21R)-N-{[4-(aminomethyl)phenyl]methyl}-21-[(benzenesulfonyl)amino]-3,11,20-trioxo-2,5,8,12,19-pentaazatetracyclo[21.2.2.2~5,8~.2~13,16~]hentriaconta-1(25),13,15,23,26,28-hexaene-18-carboxamide | non-polymer | 780.9 | 2 | Chemie (GGI) | |||
| 3 | D, E, G, H, I... (A, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | J (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 465 | Chemie (HOH) |
Sequence modifications
A, B: 542 - 791 (UniProt: P00747)
| PDB | External Database | Details |
|---|---|---|
| Ala 741 | Ser 760 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54638.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2230.3 | |
| All* | Total formula weight | 56869.1 |
