8F6Y
Cryo-EM structure of Torpedo nicotinic acetylcholine receptor in complex with etomidate, desensitized-like state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Acetylcholine receptor subunit alpha | polymer | 433 | 49766.8 | 2 | UniProt (P02710) Pfam (PF02931) Pfam (PF02932) | Tetronarce californica (Pacific electric ray) | |
| 2 | B (B) | Acetylcholine receptor subunit delta | polymer | 500 | 57554.6 | 1 | UniProt (P02718) Pfam (PF02931) Pfam (PF02932) | Tetronarce californica (Pacific electric ray) | |
| 3 | C (C) | Acetylcholine receptor subunit beta | polymer | 469 | 53731.8 | 1 | UniProt (P02712) Pfam (PF02931) Pfam (PF02932) | Tetronarce californica (Pacific electric ray) | |
| 4 | E (E) | Acetylcholine receptor subunit gamma | polymer | 489 | 56335.7 | 1 | UniProt (P02714) Pfam (PF02931) Pfam (PF02932) | Tetronarce californica (Pacific electric ray) | |
| 5 | F, I, J (F, I, J) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G94626GC) | |||
| 6 | G (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 7 | H (H) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 8 | K, S (A, D) | Etomidate | non-polymer | 244.3 | 2 | Chemie (V8D) | |||
| 9 | L, T (A, D) | CHOLINE ION | non-polymer | 104.2 | 2 | Chemie (CHT) | |||
| 10 | M, R, U (A, C, D) | CHOLESTEROL | non-polymer | 386.7 | 3 | Chemie (CLR) | |||
| 11 | N, X (B, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 12 | O, P, Q, V, Y... (B, C, D, E) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 6 | Chemie (POV) | |||
| 13 | W (D) | nonane | non-polymer | 128.3 | 1 | Chemie (DD9) | |||
| 14 | AA, BA, CA (A, B, D) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 267155.7 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 3743.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 6988.0 | |
| All* | Total formula weight | 277887.1 |
