8F6G
Crystal structure of BPTF bromodomain in complex with BZ2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nucleosome-remodeling factor subunit BPTF | polymer | 123 | 14455.4 | 1 | UniProt (Q12830) Pfam (PF00439) | Homo sapiens (human) | Bromodomain and PHD finger-containing transcription factor,Fetal Alz-50 clone 1 protein,Fetal Alzheimer antigen |
| 2 | B (A) | 6-[4-(2-aminoethyl)anilino]-5-chloro-3-methylpyrimidin-4(3H)-one | non-polymer | 278.7 | 1 | Chemie (XHK) | |||
| 3 | C (A) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A: 2917 - 3037 (UniProt: Q12830)
| PDB | External Database | Details |
|---|---|---|
| Ser 2915 | - | expression tag |
| Met 2916 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14455.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 278.7 | |
| All* | Total formula weight | 14734.2 |
