8F5J
human branched chain ketoacid dehydrogenase kinase in complex with inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | polymer | 388 | 44251.6 | 1 | UniProt (O14874) Pfam (PF10436) Pfam (PF02518) In PDB | Homo sapiens (human) | Branched-chain alpha-ketoacid dehydrogenase kinase,BCKD-kinase,BCKDHKIN |
| 2 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 5 | A | 3-chloro-5-fluorothieno[3,2-b]thiophene-2-carboxylic acid | non-polymer | 236.7 | 1 | Chemie (XER) | |||
| 6 | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
A: 1 - 382 (UniProt: O14874)
| PDB | External Database | Details |
|---|---|---|
| His 383 | - | expression tag |
| His 384 | - | expression tag |
| His 385 | - | expression tag |
| His 386 | - | expression tag |
| His 387 | - | expression tag |
| His 388 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44251.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 727.3 | |
| All* | Total formula weight | 44978.9 |
