8F5I

SARS-CoV-2 S2 helix epitope scaffold bound by antibody DH1057.1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Specialized acyl carrier protein	polymer	101	11333.7	2	UniProt (Q6N882) Pfam (PF00550) In PDB	Rhodopseudomonas palustris
2	H, X	DH1057.1 HC	polymer	227	24102.9	2		Homo sapiens
3	L, Y	DH1057.1 LC	polymer	216	23638.3	2		Homo sapiens
4	C	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G22768VO)
5	I	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
6		water	water		18.0	1353	Chemie (HOH)

Sequence modifications

A, B: 1 - 93 (UniProt: Q6N882)

PDB	External Database	Details
Ala 16	Cys 16	conflict
Glu 37	Ser 37	conflict
Ser 54	Lys 54	conflict
Phe 58	Glu 58	conflict
Glu 61	Thr 61	conflict
Leu 62	Gln 62	conflict
Asp 63	Glu 63	conflict
Tyr 65	Asn 65	conflict
Phe 66	Asp 66	conflict
Ser 68	Lys 68	conflict
Leu 94	-	expression tag
Glu 95	-	expression tag
His 96	-	expression tag
His 97	-	expression tag
His 98	-	expression tag
His 99	-	expression tag
His 100	-	expression tag
His 101	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	118149.9
Branched	Number of molecules	2
	Total formula weight	1659.5
All*	Total formula weight	119809.4

*Water molecules are not included.