8F4Q
rat branched chain ketoacid dehydrogenase kinase in complex with inhibtors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | polymer | 388 | 44261.6 | 1 | UniProt (Q00972) Pfam (PF10436) Pfam (PF02518) | Rattus | Branched-chain alpha-ketoacid dehydrogenase kinase,BCKD-kinase,BCKDHKIN |
| 2 | B (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E, F, G (A) | 3-chloro-5-fluorothieno[3,2-b]thiophene-2-carboxylic acid | non-polymer | 236.7 | 3 | Chemie (XER) | |||
| 5 | H (A) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
A: 1 - 382 (UniProt: Q00972)
| PDB | External Database | Details |
|---|---|---|
| His 383 | - | expression tag |
| His 384 | - | expression tag |
| His 385 | - | expression tag |
| His 386 | - | expression tag |
| His 387 | - | expression tag |
| His 388 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44261.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1329.3 | |
| All* | Total formula weight | 45590.9 |
