8F3U
Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I V629E variant penicillin bound form from Enterococcus faecium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Penicillin binding protein 5 | polymer | 645 | 70188.2 | 1 | UniProt (G5CKR9) Pfam (PF05223) Pfam (PF03717) Pfam (PF00905) In PDB | Enterococcus faecium | Penicillin-binding protein Pbp5 |
| 2 | A | OPEN FORM - PENICILLIN G | non-polymer | 336.4 | 1 | Chemie (PNM) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 21 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 234 | Chemie (HOH) |
Sequence modifications
A: 37 - 678 (UniProt: G5CKR9)
| PDB | External Database | Details |
|---|---|---|
| Gly 34 | - | expression tag |
| His 35 | - | expression tag |
| Met 36 | - | expression tag |
| Met 485 | Thr 485 | engineered mutation |
| Ile 499 | Thr 499 | engineered mutation |
| Val 586 | Leu 586 | conflict |
| Glu 629 | Val 629 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 70188.2 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 2353.7 | |
| All* | Total formula weight | 72541.9 |
