8F2S
Cryo-EM structure of Torpedo nicotinic acetylcholine receptor in complex with rocuronium, pore-blocked state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Acetylcholine receptor subunit alpha | polymer | 433 | 49766.8 | 2 | UniProt (P02710) Pfam (PF02931) Pfam (PF02932) | Tetronarce californica (Pacific electric ray) | |
| 2 | B (B) | Acetylcholine receptor subunit delta | polymer | 500 | 57554.6 | 1 | UniProt (P02718) Pfam (PF02931) Pfam (PF02932) | Tetronarce californica (Pacific electric ray) | |
| 3 | C (C) | Acetylcholine receptor subunit beta | polymer | 469 | 53731.8 | 1 | UniProt (P02712) Pfam (PF02931) Pfam (PF02932) | Tetronarce californica (Pacific electric ray) | |
| 4 | E (E) | Acetylcholine receptor subunit gamma | polymer | 489 | 56335.7 | 1 | UniProt (P02714) Pfam (PF02931) Pfam (PF02932) | Tetronarce californica (Pacific electric ray) | |
| 5 | F (F) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G55220VL) | |||
| 6 | G (G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 7 | H (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 8 | I, J (I, J) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G94626GC) | |||
| 9 | K, P, U (A, B, D) | rocuronium | non-polymer | 529.8 | 3 | Chemie (RBR) | |||
| 10 | L, R, S, T, Y... (A, B, C, E) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 6 | Chemie (POV) | |||
| 11 | M, V, W (A, D) | CHOLESTEROL | non-polymer | 386.7 | 3 | Chemie (CLR) | |||
| 12 | N, O, X (B, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 13 | Q (B) | nonane | non-polymer | 128.3 | 1 | Chemie (DD9) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 267155.7 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 4067.7 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 8101.6 | |
| All* | Total formula weight | 279325.0 |
