8F1F
Structure of K48-linked tri-ubiquitin in complex with cyclic peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, a) | Ubiquitin | polymer | 77 | 8691.9 | 2 | UniProt (P0CG47) Pfam (PF00240) | Homo sapiens (human) | |
| 2 | B, E (B, b) | Ubiquitin | polymer | 76 | 8576.8 | 2 | UniProt (P0CG47) Pfam (PF00240) | Homo sapiens (human) | |
| 3 | C, F (C, c) | Ubiquitin | polymer | 76 | 8604.8 | 2 | UniProt (P0CG47) Pfam (PF00240) | Homo sapiens (human) | |
| 4 | G, H (1, 2) | Non-proteinogenic cyclic peptide (inhibitor) | polymer | 14 | 1487.7 | 2 | Homo sapiens | ||
| 5 | I (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | J, K (B, b) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 7 | L, M, N, O, P... (A, B, C, a, b...) | water | water | 18.0 | 299 | Chemie (HOH) |
Sequence modifications
A, a: 1 - 76 (UniProt: P0CG47)
C, c: 1 - 76 (UniProt: P0CG47)
| PDB | External Database | Details |
|---|---|---|
| Asp 77 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Arg 48 | Lys 48 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 54722.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 568.7 | |
| All* | Total formula weight | 55291.4 |
