8F18

Apo KIF20A[1-565] class-2 in complex with a microtubule

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tubulin alpha-1B chain	polymer	451	50204.4	1	UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) In PDB	Sus scrofa (pig)	Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain
2	B	Tubulin beta-2B chain	polymer	445	49999.9	1	UniProt (A0A287AGU7) Pfam (PF00091) Pfam (PF03953) In PDB	Sus scrofa (pig)
3	K	Kinesin-like protein KIF20A	polymer	573	64088.2	1	UniProt (P97329) Pfam (PF00225) In PDB	Mus musculus (house mouse)	Kinesin-like protein 174,Rab6-interacting kinesin-like protein,Rabkinesin-6
4	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	A	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	1	Chemie (GTP)
6	B	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
7	B	TAXOL	non-polymer		853.9	1	Chemie (TA1)

Sequence modifications

K: 1 - 565 (UniProt: P97329)

PDB	External Database	Details
Leu 566	-	expression tag
Glu 567	-	expression tag
His 568	-	expression tag
His 569	-	expression tag
His 570	-	expression tag
His 571	-	expression tag
His 572	-	expression tag
His 573	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	164292.5
Non-Polymers*	Number of molecules	4
	Total formula weight	1844.6
All*	Total formula weight	166137.1

*Water molecules are not included.