8F13
Structure of the MDM2 P53 binding domain in complex with H103, an all-D Helicon Polypeptide, alternative C-terminus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | E3 ubiquitin-protein ligase Mdm2 | polymer | 95 | 11099.0 | 1 | UniProt (Q00987) Pfam (PF02201) In PDB | Homo sapiens (human) | Double minute 2 protein,Hdm2,Oncoprotein Mdm2,RING-type E3 ubiquitin transferase Mdm2,p53-binding protein Mdm2 |
| 2 | B | H103 | polymer | 19 | 1976.3 | 1 | synthetic construct | ||
| 3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | B | N,N'-(1,4-phenylene)diacetamide | non-polymer | 192.2 | 1 | Chemie (WHL) | |||
| 7 | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 13075.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 738.8 | |
| All* | Total formula weight | 13814.1 |
