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8F13

Structure of the MDM2 P53 binding domain in complex with H103, an all-D Helicon Polypeptide, alternative C-terminus

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase Mdm2polymer9511099.01UniProt (Q00987)
Pfam (PF02201)
Homo sapiens (human)Double minute 2 protein,Hdm2,Oncoprotein Mdm2,RING-type E3 ubiquitin transferase Mdm2,p53-binding protein Mdm2
2B
(B)
H103polymer191976.31synthetic construct
3C, D, E, F, J...
(A, B)
1,2-ETHANEDIOLnon-polymer62.16Chemie (EDO)
4G
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
5H
(A)
DIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
6I
(B)
N,N'-(1,4-phenylene)diacetamidenon-polymer192.21Chemie (WHL)
7L, M
(A, B)
waterwater18.0150Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight13075.3
Non-Polymers*Number of molecules9
Total formula weight738.8
All*Total formula weight13814.1
*Water molecules are not included.

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PDB entries from 2025-10-15

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