8EZB
NHEJ Long-range complex with ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, J (A, J) | X-ray repair cross-complementing protein 6 | polymer | 609 | 69945.0 | 2 | UniProt (P12956) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF02037) | Homo sapiens (human) | 5'-deoxyribose-5-phosphate lyase Ku70,5'-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit,CTCBF,DNA repair protein XRCC6,Lupus Ku autoantigen protein p70,Ku70,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 6 |
| 2 | B, K (B, K) | X-ray repair cross-complementing protein 5 | polymer | 732 | 82812.4 | 2 | UniProt (P13010) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF08785) | Homo sapiens (human) | 86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit,CTCBF,DNA repair protein XRCC5,Ku80,Ku86,Lupus Ku autoantigen protein p86,Nuclear factor IV,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| 3 | C, L (C, L) | DNA-dependent protein kinase catalytic subunit | polymer | 4128 | 469673.2 | 2 | UniProt (P78527) Pfam (PF08163) Pfam (PF19704) Pfam (PF02259) Pfam (PF00454) Pfam (PF02260) Pfam (PF20502) | Homo sapiens (human) | DNA-PKcs,DNPK1,p460 |
| 4 | D, M (D, M) | DNA (31-MER) | polymer | 31 | 9510.2 | 2 | Homo sapiens | ||
| 5 | E, N (E, N) | DNA (30-MER) | polymer | 30 | 9237.0 | 2 | Homo sapiens | ||
| 6 | F, G, O, P (F, G, O, P) | DNA repair protein XRCC4 | polymer | 336 | 38337.7 | 4 | UniProt (Q13426) Pfam (PF06632) Pfam (PF21924) Pfam (PF21925) | Homo sapiens (human) | X-ray repair cross-complementing protein 4 |
| 7 | H, I (H, I) | Non-homologous end-joining factor 1 | polymer | 299 | 33372.2 | 2 | UniProt (Q9H9Q4) Pfam (PF09302) Pfam (PF21928) | Homo sapiens (human) | Protein cernunnos,XRCC4-like factor |
| 8 | Q, R (S, T) | Protein PAXX | polymer | 204 | 21663.5 | 2 | UniProt (Q9BUH6) Pfam (PF15384) | Homo sapiens (human) | Paralog of XRCC4 and XLF,XRCC4-like small protein |
| 9 | S, T (X, Y) | DNA ligase 4 | polymer | 911 | 104125.0 | 2 | UniProt (P49917) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) Pfam (PF00533) Pfam (PF11411) | Homo sapiens (human) | DNA ligase IV,Polydeoxyribonucleotide synthase [ATP] 4 |
| 10 | U, W (C, L) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 11 | V, X (C, L) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 1754027.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1063.0 | |
| All* | Total formula weight | 1755090.8 |
