8EZ4
Plasmodium falciparum M17 in complex with inhibitor 9aa
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | M17 leucyl aminopeptidase | polymer | 527 | 58577.8 | 12 | UniProt (Q8IL11) Pfam (PF00883) In PDB | Plasmodium falciparum (malaria parasite P. falciparum) | |
2 | F, L, C, I, D... | N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-N~2~-phenylglycinamide | non-polymer | 429.4 | 12 | Chemie (X10) | |||
3 | F, L, C, I, G... | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
4 | F, L, C, I, D... | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 30 | Chemie (1PE) | |||
5 | L, C, F, I, D... | CARBONATE ION | non-polymer | 60.0 | 12 | Chemie (CO3) | |||
6 | B, E, H, L, C... | ZINC ION | non-polymer | 65.4 | 24 | Chemie (ZN) | |||
7 | K, B, H, F, I... | SODIUM ION | non-polymer | 23.0 | 9 | Chemie (NA) | |||
8 | H | NONAETHYLENE GLYCOL | non-polymer | 414.5 | 1 | Chemie (2PE) | |||
9 | water | water | 18.0 | 4701 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 85 - 605 (UniProt: Q8IL11)
PDB | External Database | Details |
---|---|---|
Gln 152 | Asn 152 | conflict |
Gln 515 | Asn 515 | conflict |
Gln 546 | Asn 546 | conflict |
His 606 | - | expression tag |
His 607 | - | expression tag |
His 608 | - | expression tag |
His 609 | - | expression tag |
His 610 | - | expression tag |
His 611 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 702933.3 | |
Non-Polymers* | Number of molecules | 101 |
Total formula weight | 16461.2 | |
All* | Total formula weight | 719394.5 |