8EZ2
Plasmodium falciparum M1 in complex with inhibitor 15ag
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | M1 family aminopeptidase | polymer | 898 | 104834.0 | 1 | UniProt (O96935) Pfam (PF17900) Pfam (PF01433) Pfam (PF11940) Pfam (PF17432) | Plasmodium falciparum (malaria parasite P. falciparum) | Pfa-M1 |
| 2 | B, F, G, H, I... (A) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 3 | C, E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 4 | D (A) | N-[(1R)-1-(4-bromophenyl)-2-(hydroxyamino)-2-oxoethyl]-N~2~-(3-fluorophenyl)glycinamide | non-polymer | 396.2 | 1 | Chemie (X68) | |||
| 5 | K (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | L, M (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 7 | N (A) | water | water | 18.0 | 933 | Chemie (HOH) |
Sequence modifications
A: 195 - 1085 (UniProt: O96935)
| PDB | External Database | Details |
|---|---|---|
| Met 194 | - | initiating methionine |
| Gln 213 | Asn 213 | conflict |
| Gln 223 | Asn 223 | conflict |
| Pro 378 | His 378 | conflict |
| Gln 501 | Asn 501 | conflict |
| Gln 745 | Asn 745 | conflict |
| Gln 795 | Asn 795 | conflict |
| Gln 1069 | Asn 1069 | conflict |
| His 1086 | - | expression tag |
| His 1087 | - | expression tag |
| His 1088 | - | expression tag |
| His 1089 | - | expression tag |
| His 1090 | - | expression tag |
| His 1091 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 104834.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1219.1 | |
| All* | Total formula weight | 106053.0 |
