8EYE
Plasmodium falciparum M1 in complex with inhibitor 9aj
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | M1 family aminopeptidase | polymer | 898 | 104834.0 | 1 | UniProt (O96935) Pfam (PF17900) Pfam (PF01433) Pfam (PF11940) Pfam (PF17432) | Plasmodium falciparum (malaria parasite P. falciparum) | Pfa-M1 |
| 2 | B, C, E, I, J... (A) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 3 | D, F, H, K (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
| 4 | G (A) | N~2~-(3,5-difluorophenyl)-N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]glycinamide | non-polymer | 465.4 | 1 | Chemie (X4I) | |||
| 5 | M (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | N, O, P, Q (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 7 | R (A) | water | water | 18.0 | 1140 | Chemie (HOH) |
Sequence modifications
A: 195 - 1085 (UniProt: O96935)
| PDB | External Database | Details |
|---|---|---|
| Met 194 | - | initiating methionine |
| Gln 213 | Asn 213 | conflict |
| Gln 223 | Asn 223 | conflict |
| Pro 378 | His 378 | conflict |
| Gln 501 | Asn 501 | conflict |
| Gln 745 | Asn 745 | conflict |
| Gln 795 | Asn 795 | conflict |
| Gln 1069 | Asn 1069 | conflict |
| His 1086 | - | expression tag |
| His 1087 | - | expression tag |
| His 1088 | - | expression tag |
| His 1089 | - | expression tag |
| His 1090 | - | expression tag |
| His 1091 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 104834.0 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1493.1 | |
| All* | Total formula weight | 106327.1 |
