8EXX
Herpes simplex virus 1 polymerase holoenzyme bound to DNA and foscarnet (pre-translocation state)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA polymerase | polymer | 1199 | 133614.3 | 1 | UniProt (H9E937) In PDB | Human alphaherpesvirus 1 strain KOS | |
2 | B | DNA polymerase processivity factor | polymer | 340 | 36346.2 | 1 | UniProt (H9E949) In PDB | Human alphaherpesvirus 1 strain KOS | Polymerase accessory protein |
3 | P | Primer DNA (32-MER) | polymer | 32 | 9866.4 | 1 | synthetic construct | ||
4 | T | Template DNA (50-MER) | polymer | 50 | 15223.8 | 1 | synthetic construct | ||
5 | A | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
6 | A | PHOSPHONOFORMIC ACID | non-polymer | 126.0 | 1 | Chemie (PPF) |
Sequence modifications
A: 43 - 1235 (UniProt: H9E937)
PDB | External Database | Details |
---|---|---|
His 37 | - | expression tag |
His 38 | - | expression tag |
His 39 | - | expression tag |
His 40 | - | expression tag |
His 41 | - | expression tag |
His 42 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 195050.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 198.9 | |
All* | Total formula weight | 195249.6 |