8EWB
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure III
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (BA) | 40S ribosomal protein S0-A | polymer | 252 | 28051.3 | 1 | UniProt (P32905) Pfam (PF00318) | Saccharomyces cerevisiae (baker's yeast) | Nucleic acid-binding protein NAB1A,Small ribosomal subunit protein uS2-A |
| 2 | B (BB) | RPS1A isoform 1 | polymer | 255 | 28798.5 | 1 | UniProt (A0A6A5PRY4) | Saccharomyces cerevisiae (baker's yeast) | |
| 3 | C (BC) | RPS2 isoform 1 | polymer | 254 | 27490.8 | 1 | UniProt (A0A6A5PWF7) | Saccharomyces cerevisiae (baker's yeast) | |
| 4 | D (BE) | 40S ribosomal protein S4-A | polymer | 261 | 29469.3 | 1 | UniProt (P0CX35) Pfam (PF08071) Pfam (PF01479) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) | Saccharomyces cerevisiae (baker's yeast) | RP5,S7,Small ribosomal subunit protein eS4-A,YS6 |
| 5 | E (BG) | 40S ribosomal protein S6-A | polymer | 236 | 27054.5 | 1 | UniProt (P0CX37) Pfam (PF01092) | Saccharomyces cerevisiae (baker's yeast) | RP9,S10,Small ribosomal subunit protein eS6-A,YS4 |
| 6 | F (BH) | 40S ribosomal protein S7-A | polymer | 190 | 21658.2 | 1 | UniProt (P26786) Pfam (PF01251) | Saccharomyces cerevisiae (baker's yeast) | RP30,RP40,Small ribosomal subunit protein eS7-A |
| 7 | G (BI) | 40S ribosomal protein S8-A | polymer | 200 | 22537.8 | 1 | UniProt (P0CX39) Pfam (PF01201) | Saccharomyces cerevisiae (baker's yeast) | RP19,S14,Small ribosomal subunit protein eS8-A,YS9 |
| 8 | H (BJ) | 40S ribosomal protein S9-A | polymer | 197 | 22487.9 | 1 | UniProt (O13516) Pfam (PF00163) Pfam (PF01479) | Saccharomyces cerevisiae (baker's yeast) | RP21,S13,Small ribosomal subunit protein uS4-A,YP28,YS11 |
| 9 | I (BL) | 40S ribosomal protein S11-A | polymer | 156 | 17785.9 | 1 | UniProt (P0CX47) Pfam (PF16205) Pfam (PF00366) | Saccharomyces cerevisiae (baker's yeast) | RP41,S18,Small ribosomal subunit protein uS17-A,YS12 |
| 10 | J (BN) | 40S ribosomal protein S13 | polymer | 151 | 17059.9 | 1 | UniProt (P05756) Pfam (PF08069) Pfam (PF00312) | Saccharomyces cerevisiae (baker's yeast) | S27a,Small ribosomal subunit protein uS15,YS15 |
| 11 | K (BO) | 40S ribosomal protein S14-A | polymer | 137 | 14562.7 | 1 | UniProt (P06367) Pfam (PF00411) | Saccharomyces cerevisiae (baker's yeast) | RP59A,Small ribosomal subunit protein uS11-A |
| 12 | L (BV) | 40S ribosomal protein S21-A | polymer | 87 | 9758.8 | 1 | UniProt (P0C0V8) Pfam (PF01249) | Saccharomyces cerevisiae (baker's yeast) | S26,Small ribosomal subunit protein eS21-A,YS25 |
| 13 | M (BW) | RPS22A isoform 1 | polymer | 130 | 14650.1 | 1 | UniProt (A0A6A5PSE9) | Saccharomyces cerevisiae (baker's yeast) | |
| 14 | N (BX) | 40S ribosomal protein S23-A | polymer | 145 | 16073.9 | 1 | UniProt (P0CX29) Pfam (PF00164) | Saccharomyces cerevisiae (baker's yeast) | RP37,S28,Small ribosomal subunit protein uS12-A,YS14 |
| 15 | O (BY) | 40S ribosomal protein S24-A | polymer | 135 | 15362.8 | 1 | UniProt (P0CX31) Pfam (PF01282) | Saccharomyces cerevisiae (baker's yeast) | RP50,Small ribosomal subunit protein eS24-A |
| 16 | P (Ba) | RPS26B isoform 1 | polymer | 119 | 13480.9 | 1 | UniProt (A0A6A5Q0E8) | Saccharomyces cerevisiae (baker's yeast) | |
| 17 | Q (Bb) | 40S ribosomal protein S27-A | polymer | 82 | 8893.4 | 1 | UniProt (P35997) Pfam (PF01667) | Saccharomyces cerevisiae (baker's yeast) | RP61,Small ribosomal subunit protein eS27-A,YS20 |
| 18 | R (Be) | 40S ribosomal protein S30-A | polymer | 63 | 7137.5 | 1 | UniProt (P0CX33) Pfam (PF04758) | Saccharomyces cerevisiae (baker's yeast) | Small ribosomal subunit protein eS30-A |
| 19 | S (BD) | RPS3 isoform 1 | polymer | 240 | 26542.8 | 1 | UniProt (A0A6A5Q3Q1) | Saccharomyces cerevisiae (baker's yeast) | |
| 20 | T (BF) | Rps5p | polymer | 225 | 25072.6 | 1 | UniProt (A0A1L4AA68) | Saccharomyces cerevisiae (baker's yeast) | |
| 21 | U (BK) | 40S ribosomal protein S10-A | polymer | 105 | 12757.4 | 1 | UniProt (Q08745) Pfam (PF03501) | Saccharomyces cerevisiae (baker's yeast) | Small ribosomal subunit protein eS10-A |
| 22 | V (BP) | RPS15 isoform 1 | polymer | 142 | 16031.9 | 1 | UniProt (A0A6A5Q6F2) | Saccharomyces cerevisiae (baker's yeast) | |
| 23 | W (BQ) | 40S ribosomal protein S16-A | polymer | 143 | 15877.5 | 1 | UniProt (P0CX51) Pfam (PF00380) | Saccharomyces cerevisiae (baker's yeast) | RP61R,Small ribosomal subunit protein uS9-A |
| 24 | X (BR) | 40S ribosomal protein S17-A | polymer | 136 | 15820.4 | 1 | UniProt (P02407) Pfam (PF00833) | Saccharomyces cerevisiae (baker's yeast) | RP51A,Small ribosomal subunit protein eS17-A |
| 25 | Y (BS) | 40S ribosomal protein S18-A | polymer | 146 | 17071.6 | 1 | UniProt (P0CX55) Pfam (PF00416) | Saccharomyces cerevisiae (baker's yeast) | Small ribosomal subunit protein uS13-A |
| 26 | Z (BT) | 40S ribosomal protein S19-A | polymer | 144 | 15942.1 | 1 | UniProt (P07280) Pfam (PF01090) | Saccharomyces cerevisiae (baker's yeast) | RP55A,S16a,Small ribosomal subunit protein eS19-A,YP45,YS16A |
| 27 | AA (BU) | RPS20 isoform 1 | polymer | 121 | 13929.0 | 1 | UniProt (A0A6A5PVE9) | Saccharomyces cerevisiae (baker's yeast) | |
| 28 | BA (BZ) | RPS25A isoform 1 | polymer | 108 | 12067.3 | 1 | UniProt (A0A6A5PZ18) | Saccharomyces cerevisiae (baker's yeast) | |
| 29 | CA (Bc) | RPS28A isoform 1 | polymer | 67 | 7605.8 | 1 | UniProt (A0A6A5Q700) | Saccharomyces cerevisiae (baker's yeast) | |
| 30 | DA (Bd) | RPS29A isoform 1 | polymer | 56 | 6675.7 | 1 | UniProt (A0A6A5PV92) | Saccharomyces cerevisiae (baker's yeast) | |
| 31 | EA (Bg) | Guanine nucleotide-binding protein subunit beta-like protein | polymer | 319 | 34841.2 | 1 | UniProt (P38011) Pfam (PF00400) | Saccharomyces cerevisiae (baker's yeast) | Receptor for activated C kinase,Receptor of activated protein kinase C 1,RACK1,Small ribosomal subunit protein RACK1 |
| 32 | FA (Bf) | Ubiquitin-40S ribosomal protein S31 | polymer | 152 | 17254.2 | 1 | UniProt (A0A6A5PU37) | Saccharomyces cerevisiae (baker's yeast) | |
| 33 | GA (BM) | 40S ribosomal protein S12 | polymer | 143 | 15488.6 | 1 | UniProt (A0A6A5Q8I3) | Saccharomyces cerevisiae (baker's yeast) | |
| 34 | HA (B5) | 18S rRNA | polymer | 1798 | 579649.3 | 1 | GenBank (1329886537) | Saccharomyces cerevisiae (baker's yeast) | |
| 35 | IA (AA) | 60S ribosomal protein L2-A | polymer | 254 | 27463.6 | 1 | UniProt (P0CX45) Pfam (PF00181) Pfam (PF03947) | Saccharomyces cerevisiae (baker's yeast) | L5,Large ribosomal subunit protein uL2-A,RP8,YL6 |
| 36 | JA (AB) | 60S ribosomal protein L3 | polymer | 387 | 43863.8 | 1 | UniProt (P14126) Pfam (PF00297) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein uL3,Maintenance of killer protein 8,RP1,Trichodermin resistance protein,YL1 |
| 37 | KA (AC) | RPL4A isoform 1 | polymer | 362 | 39159.1 | 1 | UniProt (A0A6A5Q3W0) | Saccharomyces cerevisiae (baker's yeast) | |
| 38 | LA (A1) | 25S rRNA | polymer | 3360 | 1086493.1 | 1 | Saccharomyces cerevisiae | ||
| 39 | MA (A3) | 5s rRNA | polymer | 121 | 38951.1 | 1 | GenBank (1039024045) | Saccharomyces cerevisiae (baker's yeast) | |
| 40 | NA (A4) | 5.8 S rRNA | polymer | 158 | 50682.9 | 1 | GenBank (1267176496) | Saccharomyces cerevisiae (baker's yeast) | |
| 41 | OA (AD) | RPL5 isoform 1 | polymer | 297 | 33764.8 | 1 | UniProt (A0A6A5Q0W8) | Saccharomyces cerevisiae (baker's yeast) | |
| 42 | PA (AE) | 60S ribosomal protein L6-A | polymer | 176 | 20000.6 | 1 | UniProt (Q02326) Pfam (PF01159) | Saccharomyces cerevisiae (baker's yeast) | L17,Large ribosomal subunit protein eL6-A,RP18,YL16 |
| 43 | QA (AF) | 60S ribosomal protein L7-A | polymer | 244 | 27686.3 | 1 | UniProt (P05737) Pfam (PF08079) Pfam (PF00327) | Saccharomyces cerevisiae (baker's yeast) | L6,Large ribosomal subunit protein uL30-A,RP11,YL8 |
| 44 | RA (AG) | 60S ribosomal protein L8-A | polymer | 256 | 28175.8 | 1 | UniProt (P17076) Pfam (PF01248) | Saccharomyces cerevisiae (baker's yeast) | L4,L4-2,L7a-1,Large ribosomal subunit protein eL8-A,Maintenance of killer protein 7,RP6,YL5 |
| 45 | SA (AH) | 60S ribosomal protein L9-A | polymer | 191 | 21605.1 | 1 | UniProt (P05738) Pfam (PF00347) | Saccharomyces cerevisiae (baker's yeast) | L8,Large ribosomal subunit protein uL6-A,RP24,YL11 |
| 46 | TA (AI) | RPL10 isoform 1 | polymer | 221 | 25410.5 | 1 | UniProt (A0A6A5PUZ5) | Saccharomyces cerevisiae (baker's yeast) | |
| 47 | UA (AJ) | RPL11A isoform 1 | polymer | 174 | 19755.7 | 1 | UniProt (A0A6A5Q7I9) | Saccharomyces cerevisiae (baker's yeast) | |
| 48 | VA (AL) | 60S ribosomal protein L13-A | polymer | 199 | 22604.2 | 1 | UniProt (Q12690) Pfam (PF01294) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein eL13-A |
| 49 | WA (AM) | 60S ribosomal protein L14-A | polymer | 138 | 15195.1 | 1 | UniProt (P36105) Pfam (PF00467) Pfam (PF01929) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein eL14-A |
| 50 | XA (AN) | 60S ribosomal protein L15-A | polymer | 204 | 24482.4 | 1 | UniProt (P05748) Pfam (PF00827) | Saccharomyces cerevisiae (baker's yeast) | L13,Large ribosomal subunit protein eL15-A,RP15R,YL10,YP18 |
| 51 | YA (AO) | 60S ribosomal protein L16-A | polymer | 199 | 22247.2 | 1 | UniProt (P26784) Pfam (PF00572) | Saccharomyces cerevisiae (baker's yeast) | L13a,L21,Large ribosomal subunit protein uL13-A,RP22,YL15 |
| 52 | ZA (AP) | 60S ribosomal protein L17-A | polymer | 184 | 20589.5 | 1 | UniProt (P05740) Pfam (PF00237) | Saccharomyces cerevisiae (baker's yeast) | L20A,Large ribosomal subunit protein uL22-A,YL17 |
| 53 | AB (AQ) | 60S ribosomal protein L18-A | polymer | 186 | 20609.3 | 1 | UniProt (P0CX49) Pfam (PF17135) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein eL18-A,RP28 |
| 54 | BB (AR) | 60S ribosomal protein L19-A | polymer | 189 | 21762.3 | 1 | UniProt (P0CX82) Pfam (PF01280) Pfam (PF25476) | Saccharomyces cerevisiae (baker's yeast) | L23,Large ribosomal subunit protein eL19-A,RP15L,RP33,YL14 |
| 55 | CB (AS) | 60S ribosomal protein L20 | polymer | 178 | 21279.9 | 1 | UniProt (B3LMD0) | Saccharomyces cerevisiae (baker's yeast) | |
| 56 | DB (AT) | 60S ribosomal protein L21-A | polymer | 160 | 18279.3 | 1 | UniProt (Q02753) Pfam (PF01157) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein eL21-A |
| 57 | EB (AU) | 60S ribosomal protein L22-A | polymer | 121 | 13711.4 | 1 | UniProt (P05749) Pfam (PF01776) | Saccharomyces cerevisiae (baker's yeast) | L1c,Large ribosomal subunit protein eL22-A,RP4,YL31 |
| 58 | FB (AV) | 60S ribosomal protein L23-A | polymer | 137 | 14494.0 | 1 | UniProt (P0CX41) Pfam (PF00238) | Saccharomyces cerevisiae (baker's yeast) | L17a,Large ribosomal subunit protein uL14-A,YL32 |
| 59 | GB (AW) | RPL24A isoform 1 | polymer | 155 | 17661.7 | 1 | UniProt (A0A6A5PY83) | Saccharomyces cerevisiae (baker's yeast) | |
| 60 | HB (AX) | 60S ribosomal protein L25 | polymer | 142 | 15787.6 | 1 | UniProt (P04456) Pfam (PF03939) Pfam (PF00276) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein uL23,RP16L,YL25,YP42' |
| 61 | IB (AY) | 60S ribosomal protein L26-A | polymer | 127 | 14265.8 | 1 | UniProt (P05743) Pfam (PF16906) Pfam (PF00467) | Saccharomyces cerevisiae (baker's yeast) | L33,Large ribosomal subunit protein uL24-A,YL33 |
| 62 | JB (AZ) | 60S ribosomal protein L27-A | polymer | 136 | 15568.4 | 1 | UniProt (P0C2H6) Pfam (PF01777) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein eL27-A |
| 63 | KB (Aa) | 60S ribosomal protein L28 | polymer | 149 | 16761.7 | 1 | UniProt (P02406) Pfam (PF00828) | Saccharomyces cerevisiae (baker's yeast) | L27a,L29,Large ribosomal subunit protein uL15,RP44,RP62,YL24 |
| 64 | LB (Ab) | RPL29 isoform 1 | polymer | 59 | 6691.9 | 1 | UniProt (A0A6A5PWR1) | Saccharomyces cerevisiae (baker's yeast) | |
| 65 | MB (Ac) | 60S ribosomal protein L30 | polymer | 105 | 11430.4 | 1 | UniProt (P14120) Pfam (PF01248) | Saccharomyces cerevisiae (baker's yeast) | L32,Large ribosomal subunit protein eL30,RP73,YL38 |
| 66 | NB (Ad) | 60S ribosomal protein L31-A | polymer | 113 | 12980.2 | 1 | UniProt (P0C2H8) Pfam (PF01198) | Saccharomyces cerevisiae (baker's yeast) | L34,Large ribosomal subunit protein eL31-A,YL28 |
| 67 | OB (Ae) | RPL32 isoform 1 | polymer | 130 | 14809.4 | 1 | UniProt (A0A6A5Q1M9) | Saccharomyces cerevisiae (baker's yeast) | |
| 68 | PB (Af) | 60S ribosomal protein L33-A | polymer | 107 | 12177.1 | 1 | UniProt (P05744) Pfam (PF01247) | Saccharomyces cerevisiae (baker's yeast) | L37,Large ribosomal subunit protein eL33-A,RP47,YL37 |
| 69 | QB (Ag) | 60S ribosomal protein L34-A | polymer | 121 | 13673.2 | 1 | UniProt (P87262) Pfam (PF01199) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein eL34-A |
| 70 | RB (Ah) | 60S ribosomal protein L35-A | polymer | 120 | 13942.6 | 1 | UniProt (P0CX84) Pfam (PF00831) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein uL29-A |
| 71 | SB (Ai) | 60S ribosomal protein L36-A | polymer | 100 | 11151.3 | 1 | UniProt (P05745) Pfam (PF01158) | Saccharomyces cerevisiae (baker's yeast) | L39,Large ribosomal subunit protein eL36-A,YL39 |
| 72 | TB (Aj) | 60S ribosomal protein L37-A | polymer | 88 | 9877.4 | 1 | UniProt (P49166) Pfam (PF01907) | Saccharomyces cerevisiae (baker's yeast) | L43,Large ribosomal subunit protein eL37-A,YL35,YP55 |
| 73 | UB (Ak) | RPL38 isoform 1 | polymer | 78 | 8845.6 | 1 | UniProt (A0A6A5PUL8) | Saccharomyces cerevisiae (baker's yeast) | |
| 74 | VB (Al) | 60S ribosomal protein L39 | polymer | 51 | 6358.6 | 1 | UniProt (P04650) Pfam (PF00832) | Saccharomyces cerevisiae (baker's yeast) | L46,Large ribosomal subunit protein eL39,YL40 |
| 75 | WB (Am) | Ubiquitin-60S ribosomal protein L40 | polymer | 128 | 14583.1 | 1 | UniProt (P0CH08) Pfam (PF00240) Pfam (PF01020) | Saccharomyces cerevisiae (baker's yeast) | |
| 76 | XB (An) | 60S ribosomal protein L41-A | polymer | 25 | 3354.2 | 1 | UniProt (P0CX86) Pfam (PF05162) | Saccharomyces cerevisiae (baker's yeast) | L47,Large ribosomal subunit protein eL41-A,YL41 |
| 77 | YB (Ao) | 60S ribosomal protein L42-A | polymer | 106 | 12246.7 | 1 | UniProt (P0CX27) Pfam (PF00935) | Saccharomyces cerevisiae (baker's yeast) | L41,Large ribosomal subunit protein eL42-A,YL27,YP44 |
| 78 | ZB (Ap) | 60S ribosomal protein L43-A | polymer | 92 | 10113.0 | 1 | UniProt (P0CX25) Pfam (PF01780) | Saccharomyces cerevisiae (baker's yeast) | L37a,Large ribosomal subunit protein eL43-A,YL35 |
| 79 | AC (E) | RPL1A isoform 1 | polymer | 217 | 24524.8 | 1 | UniProt (A0A6A5Q2N7) | Saccharomyces cerevisiae (baker's yeast) | RPL1B isoform 1 |
| 80 | BC (DC) | Elongation factor 2 | polymer | 842 | 93549.3 | 1 | UniProt (P32324) Pfam (PF00009) Pfam (PF03144) Pfam (PF14492) Pfam (PF03764) Pfam (PF00679) | Saccharomyces cerevisiae (baker's yeast) | EF-2,Eukaryotic elongation factor 2,eEF2,Ribosomal translocase,Translation elongation factor 2 |
| 81 | CC (V) | 60S acidic ribosomal protein P0 | polymer | 312 | 33749.1 | 1 | UniProt (P05317) Pfam (PF00466) Pfam (PF17777) Pfam (PF00428) | Saccharomyces cerevisiae (baker's yeast) | A0,L10e,Large ribosomal subunit protein uL10 |
| 82 | DC (EC) | Taura syndrome virus (TSV) internal ribosome entry site (IRES) RNA | polymer | 202 | 64957.5 | 1 | GenBank (14701764) | Taura syndrome virus | |
| 83 | AD, AE, AF, AG, AH... (B5, A1, Ba, A3, A4...) | MAGNESIUM ION | non-polymer | 24.3 | 242 | Chemie (MG) PubChem (888) | |||
| 84 | ML (Ao) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 85 | NL (DC) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) |
Sequence modifications
B5: 1 - 1799 (GenBank: 1329886537)
EC: 6758 - 6952 (GenBank: 14701764)
| PDB | External Database | Details |
|---|---|---|
| B8n 1191 | U 468965 | conflict |
| 4ac 1280 | C 468876 | conflict |
| 4ac 1773 | C 468383 | conflict |
| PDB | External Database | Details |
|---|---|---|
| U 6953 | - | expression tag |
| A 6954 | - | expression tag |
| A 6955 | - | expression tag |
| A 6956 | - | expression tag |
| A 6957 | - | expression tag |
| C 6958 | - | expression tag |
| C 6959 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 82 |
| Total formula weight | 3312269.2 | |
| Non-Polymers* | Number of molecules | 244 |
| Total formula weight | 6390.4 | |
| All* | Total formula weight | 3318659.6 |
