8ET0
Crystal Complex of murine Cyclooxygenase-2 with alpaca nanobody F9
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Prostaglandin G/H synthase 2 | polymer | 587 | 67332.7 | 2 | UniProt (Q05769) Pfam (PF00008) Pfam (PF03098) In PDB | Mus musculus (house mouse) | Cyclooxygenase-2,COX-2,Glucocorticoid-regulated inflammatory cyclooxygenase,Gripghs,Macrophage activation-associated marker protein P71/73,PES-2,PHS II,Prostaglandin H2 synthase 2,PGHS-2,Prostaglandin-endoperoxide synthase 2,TIS10 protein |
2 | C, D | anti-cox-2 alpaca nanobody F9 | polymer | 140 | 15244.6 | 2 | Vicugna pacos (alpaca) | ||
3 | E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
4 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
5 | A, B | IBUPROFEN | non-polymer | 206.3 | 2 | Chemie (IBP) | |||
6 | water | water | 18.0 | 511 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 165154.5 | |
Branched | Number of molecules | 2 |
Total formula weight | 848.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1297.4 | |
All* | Total formula weight | 167300.7 |