8ET0
Crystal Complex of murine Cyclooxygenase-2 with alpaca nanobody F9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Prostaglandin G/H synthase 2 | polymer | 587 | 67332.7 | 2 | UniProt (Q05769) Pfam (PF00008) Pfam (PF03098) | Mus musculus (house mouse) | Cyclooxygenase-2,COX-2,Glucocorticoid-regulated inflammatory cyclooxygenase,Gripghs,Macrophage activation-associated marker protein P71/73,PES-2,PHS II,Prostaglandin H2 synthase 2,PGHS-2,Prostaglandin-endoperoxide synthase 2,TIS10 protein |
| 2 | C, D (C, D) | anti-cox-2 alpaca nanobody F9 | polymer | 140 | 15244.6 | 2 | Vicugna pacos (alpaca) | ||
| 3 | E, F (E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | G, H, J, K (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 5 | I, L (A, B) | IBUPROFEN | non-polymer | 206.3 | 2 | Chemie (IBP) | |||
| 6 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 511 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 165154.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1297.4 | |
| All* | Total formula weight | 167300.7 |
