8ESA

CryoEM structure of HLA-A2 bound to MAGEA4 (230-239) peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Beta-2-microglobulin,HLA class I antigen,MAGE-A4 peptide chimera	polymer	448	50306.2	3	UniProt (Q53Z42) Pfam (PF07654) Pfam (PF00129) UniProt (by SIFTS) (P61769) In PDB	Homo sapiens (Human)	HLA class I histocompatibility antigen,HLA class I histocompatibility antigen A alpha chain,A alpha chain,MHC class I antigen,MHC class I protein,MHC class I protein (HLA-A)

Sequence modifications

A, B, C: -143 - -20 (PDB: 8ESA)

PDB	External Database	Details
Gly -19	-	linker
Gly -18	-	linker
Gly -17	-	linker
Gly -16	-	linker
Ser -15	-	linker
Gly -14	-	linker
Gly -13	-	linker
Gly -12	-	linker
Gly -11	-	linker
Ser -10	-	linker
Gly -9	-	linker
Gly -8	-	linker
Gly -7	-	linker
Gly -6	-	linker
Ser -5	-	linker
Gly -4	-	linker
Gly -3	-	linker
Gly -2	-	linker
Gly -1	-	linker
Ser 0	-	linker

A, B, C: 1 - 276 (UniProt: Q53Z42)

PDB	External Database	Details
Cys 84	Tyr 108	conflict

A, B, C: 277 - 304 (PDB: 8ESA)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	150918.6
All*	Total formula weight	150918.6

*Water molecules are not included.