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8EMM

Composite 70S ribosome structure for "Atomistic simulations of the E. coli ribosome provide selection criteria for translationally active substrates

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(a)
23S rRNApolymer2904941811.61Escherichia coli
2B
(b)
5S rRNApolymer12038790.11GenBank (1273279017)Escherichia coli
3C
(c)
50S ribosomal protein L2polymer27329923.61UniProt (P60422)
Pfam (PF00181)
Pfam (PF03947)
Escherichia coliLarge ribosomal subunit protein uL2
4D
(d)
50S ribosomal protein L3polymer20922291.61UniProt (U9Y9G2)
Pfam (PF00297)
UniProt (by SIFTS) (P60438)
Escherichia coli
5E
(e)
50S ribosomal protein L4polymer20122121.61UniProt (A0A7U9FY55)
Pfam (PF00573)
UniProt (by SIFTS) (P60723)
Escherichia coli
6F
(f)
50S ribosomal protein L5polymer17920333.61UniProt (A0A829CFT8)
Pfam (PF00281)
Pfam (PF00673)
UniProt (by SIFTS) (P62399)
Escherichia coli
7G
(g)
50S ribosomal protein L6polymer17718932.81UniProt (A0A862ZNS7)
Pfam (PF00347)
UniProt (by SIFTS) (P0AG55)
Escherichia coli
8H
(h)
50S ribosomal protein L9polymer14915789.01UniProt (V0YZK9)
Pfam (PF01281)
Pfam (PF03948)
UniProt (by SIFTS) (P0A7R1)
Escherichia coli
9I
(i)
50S ribosomal protein L13polymer14216050.61UniProt (S1EW51)
Pfam (PF00572)
UniProt (by SIFTS) (P0AA10)
Escherichia coli
10J
(j)
50S ribosomal protein L14polymer12313565.11UniProt (S1NW45)
Pfam (PF00238)
UniProt (by SIFTS) (P0ADY3)
Escherichia coli
11K
(k)
50S ribosomal protein L15polymer14415008.51UniProt (A0A037Y8L6)
Pfam (PF00828)
UniProt (by SIFTS) (P02413)
Escherichia coli
12L
(l)
50S ribosomal protein L16polymer13615329.31UniProt (A0A7U9B8R8)
Pfam (PF00252)
UniProt (by SIFTS) (P0ADY7)
Escherichia coli
13M
(m)
50S ribosomal protein L17polymer12714393.71UniProt (A0A1X3LC97)
Pfam (PF01196)
UniProt (by SIFTS) (P0AG44)
Escherichia coli
14N
(n)
50S ribosomal protein L18polymer11712794.71UniProt (E3PKY8)
Pfam (PF00861)
UniProt (by SIFTS) (P0C018)
Escherichia coli
15O
(o)
50S ribosomal protein L19polymer11513159.31UniProt (V0AJX1)
Pfam (PF01245)
UniProt (by SIFTS) (P0A7K6)
Escherichia coli
16P
(p)
50S ribosomal protein L20polymer11813528.01UniProt (B7MAS6)
Pfam (PF00453)
UniProt (by SIFTS) (P0A7L3)
Escherichia coli
17Q
(q)
Ribosomal protein L21polymer10311586.41UniProt (A0A829CSJ4)
Pfam (PF00829)
UniProt (by SIFTS) (P0AG48)
Escherichia coli
18R
(r)
50S ribosomal protein L22polymer11012253.41UniProt (P61175)
Pfam (PF00237)
Escherichia coliLarge ribosomal subunit protein uL22
19S
(s)
50S ribosomal protein L23polymer10011222.21UniProt (A0A829CFV1)
Pfam (PF00276)
UniProt (by SIFTS) (P0ADZ0)
Escherichia coli
20T
(t)
50S ribosomal protein L24polymer10411339.31UniProt (A0A1X3KWX7)
Pfam (PF00467)
Pfam (PF17136)
UniProt (by SIFTS) (P60624)
Escherichia coli
21U
(u)
50S ribosomal protein L25polymer9410713.51UniProt (D7XH79)
Pfam (PF01386)
UniProt (by SIFTS) (P68919)
Escherichia coli
22V
(v)
50S ribosomal protein L27polymer859146.51UniProt (P0A7L8)
Pfam (PF01016)
Escherichia coliLarge ribosomal subunit protein bL27
23W
(w)
50S ribosomal protein L28polymer789027.61UniProt (A0A1X3JA73)
Pfam (PF00830)
UniProt (by SIFTS) (P0A7M2)
Escherichia coli
24X
(x)
50S ribosomal protein L29polymer637286.51UniProt (D6IEL0)
Pfam (PF00831)
UniProt (by SIFTS) (P0A7M6)
Escherichia coli
25Y
(y)
50S ribosomal protein L30polymer596554.81UniProt (V0YKA9)
Pfam (PF00327)
UniProt (by SIFTS) (P0AG51)
Escherichia coli
26Z
(z)
50S ribosomal protein L32polymer576463.41UniProt (D7XI28)
Pfam (PF01783)
UniProt (by SIFTS) (P0A7N4)
Escherichia coli
27AA
(0)
50S ribosomal protein L33polymer556388.61UniProt (F4NQ61)
Pfam (PF00471)
UniProt (by SIFTS) (P0A7N9)
Escherichia coli
28BA
(1)
50S ribosomal protein L34polymer465397.51UniProt (B7MGC4)
Pfam (PF00468)
UniProt (by SIFTS) (P0A7P5)
Escherichia coli
29CA
(2)
50S ribosomal protein L35polymer657313.01UniProt (P0A7Q1)
Pfam (PF01632)
Escherichia coliLarge ribosomal subunit protein bL35,Ribosomal protein A
30DA
(3)
50S ribosomal protein L36polymer384377.41UniProt (A0A0E2L017)
Pfam (PF00444)
UniProt (by SIFTS) (P0A7Q6)
Escherichia coli
31EA
(4)
50S ribosomal protein L31polymer707887.11UniProt (P0A7M9)
Pfam (PF01197)
Escherichia coliLarge ribosomal subunit protein bL31-A
32FA, GA
(Y, Z)
Met-NH-tRNApolymer7624496.62GenBank (1848851804)Escherichia coli
33HA
(A)
16S rRNApolymer1542499873.41GenBank (1758835854)Escherichia coli
34IA
(B)
30S ribosomal protein S2polymer24126781.71UniProt (C3TPN2)
Pfam (PF00318)
UniProt (by SIFTS) (P0A7V0)
Escherichia coli
35JA
(C)
30S ribosomal protein S3polymer23326031.31UniProt (B7MCS9)
Pfam (PF07650)
Pfam (PF00189)
UniProt (by SIFTS) (P0A7V3)
Escherichia coli
36KA
(D)
30S ribosomal protein S4polymer20623514.21UniProt (P0A7V8)
Pfam (PF01479)
Pfam (PF00163)
Escherichia coli
37LA
(E)
30S ribosomal protein S5polymer16717629.41UniProt (P0A7W1)
Pfam (PF00333)
Pfam (PF03719)
Escherichia coli
38MA
(F)
30S ribosomal protein S6polymer13515727.51UniProt (P02358)
Pfam (PF01250)
Escherichia coliSmall ribosomal subunit protein bS6
39NA
(G)
30S ribosomal protein S7polymer17920055.21UniProt (P02359)
Pfam (PF00177)
Escherichia coliSmall ribosomal subunit protein uS7
40OA
(H)
30S ribosomal protein S8polymer13014146.61UniProt (D7XKZ3)
Pfam (PF00410)
UniProt (by SIFTS) (P0A7W7)
Escherichia coli
41PA
(I)
30S ribosomal protein S9polymer13014886.31UniProt (A0A1X3LT86)
Pfam (PF00380)
UniProt (by SIFTS) (P0A7X3)
Escherichia coli
42QA
(J)
30S ribosomal protein S10polymer10311755.61UniProt (V0ANK5)
Pfam (PF00338)
UniProt (by SIFTS) (P0A7R5)
Escherichia coli
43RA
(K)
30S ribosomal protein S11polymer12913872.01UniProt (A0A0H3PWX2)
Pfam (PF00411)
UniProt (by SIFTS) (P0A7R9)
Escherichia coli
44SA
(L)
30S ribosomal protein S12polymer12413814.21UniProt (A0A0F1AUC4)
Pfam (PF00164)
UniProt (by SIFTS) (P0A7S3)
Escherichia coli
45TA
(M)
30S ribosomal protein S13polymer11813128.51UniProt (A0A7U9IV78)
Pfam (PF00416)
UniProt (by SIFTS) (P0A7S9)
Escherichia coli
46UA
(N)
30S ribosomal protein S14polymer10111606.61UniProt (U9Y6H3)
Pfam (PF00253)
UniProt (by SIFTS) (P0AG59)
Escherichia coli
47VA
(O)
30S ribosomal protein S15polymer8910290.81UniProt (D8EB41)
Pfam (PF00312)
UniProt (by SIFTS) (P0ADZ4)
Escherichia coli
48WA
(P)
30S ribosomal protein S16polymer829207.61UniProt (C3SYP2)
Pfam (PF00886)
UniProt (by SIFTS) (P0A7T3)
Escherichia coli
49XA
(Q)
30S ribosomal protein S17polymer849724.51UniProt (A0A829A8C6)
Pfam (PF00366)
UniProt (by SIFTS) (P0AG63)
Escherichia coli
50YA
(R)
30S ribosomal protein S18polymer759005.51UniProt (A0A0E2KXL3)
Pfam (PF01084)
UniProt (by SIFTS) (P0A7T7)
Escherichia coli
51ZA
(S)
30S ribosomal protein S19polymer9210455.41UniProt (S1EA57)
Pfam (PF00203)
UniProt (by SIFTS) (P0A7U3)
Escherichia coli
52AB
(T)
30S ribosomal protein S20polymer879708.51UniProt (C3TRH7)
Pfam (PF01649)
UniProt (by SIFTS) (P0A7U7)
Escherichia coli
53BB
(U)
30S ribosomal protein S21polymer718524.01UniProt (A0A0E2L2J1)
Pfam (PF01165)
UniProt (by SIFTS) (P68679)
Escherichia coli
54CB
(X)
mRNApolymer289099.51Escherichia coli
55AC, AD, AE, AF, AG...
(a, A, Z, b, c...)
MAGNESIUM IONnon-polymer24.3321Chemie (MG)
56AJ, BJ, CJ, DJ, EJ...
(a, A)
SPERMIDINEnon-polymer145.217Chemie (SPD)
57NJ
(a)
SPERMINEnon-polymer202.31Chemie (SPM)
58QJ, RJ, SJ, SK, TJ...
(a, c)
POTASSIUM IONnon-polymer39.110Chemie (K)
59XK, YK
(3, 4)
ZINC IONnon-polymer65.42Chemie (ZN)
60AL, ZK
(Z, Y)
METHIONINEnon-polymer149.22Chemie (MET)
61CL
(A)
PAROMOMYCINnon-polymer615.61Chemie (PAR)
62AP, BP, CP, DP, EP...
(j, k, l, m, o...)
waterwater18.03491Chemie (HOH)
Sequence modifications
l: 1 - 136 (UniProt: A0A7U9B8R8)
PDBExternal DatabaseDetails
Ms6 82Met 82conflict
K: 1 - 129 (UniProt: A0A0H3PWX2)
PDBExternal DatabaseDetails
Ias 119Asn 119conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains55
Total formula weight2198611.3
Non-Polymers*Number of molecules354
Total formula weight11909.3
All*Total formula weight2210520.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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