8ELP
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with antibody CC12.1 Fab and nanobody Nb-C4-240
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Spike protein S1 | polymer | 205 | 23104.9 | 1 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 | |
| 2 | B | Nanobody Nb-C4-240 | polymer | 140 | 15645.1 | 1 | synthetic construct | ||
| 3 | H | CC12.1 Fab heavy chain | polymer | 220 | 23178.9 | 1 | Homo sapiens (Human) | ||
| 4 | L | CC12.1 Fab light chain | polymer | 217 | 23641.4 | 1 | Homo sapiens (Human) | ||
| 5 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A: 333 - 530 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 531 | - | expression tag |
| His 532 | - | expression tag |
| His 533 | - | expression tag |
| His 534 | - | expression tag |
| His 535 | - | expression tag |
| His 536 | - | expression tag |
| His 537 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 85570.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 85791.4 |
