8EJG
Structure of lineage VII Lassa virus glycoprotein complex (strain Togo/2016/7082)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Glycoprotein GP1 | polymer | 196 | 22180.1 | 3 | UniProt (A0A142I7X5) Pfam (PF00798) In PDB | Lassa mammarenavirus | |
| 2 | a, b, c | Glycoprotein GP2 | polymer | 165 | 19176.7 | 3 | UniProt (A0A142I7X5) Pfam (PF00798) In PDB | Lassa mammarenavirus | Pre-GP-C |
| 3 | D, M, T | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 4 | X, Y, Z, e, g... | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 15 | In PDB GlyTouCan (G15407YE) | |||
| 5 | F, O, V | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 6 | G, P, W | beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G33431MT) | |||
| 7 | d, f, K | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 3 | In PDB GlyTouCan (G07617FP) | |||
| 8 | a, b, c | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
A, B, C: 59 - 254 (UniProt: A0A142I7X5)
a, b, c: 259 - 423 (UniProt: A0A142I7X5)
| PDB | External Database | Details |
|---|---|---|
| Cys 206 | Arg 206 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Pro 328 | Glu 328 | engineered mutation |
| Cys 359 | Gly 359 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 124070.4 | |
| Branched | Number of molecules | 27 |
| Total formula weight | 18268.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1327.2 | |
| All* | Total formula weight | 143666.4 |
