8EJF

Structure of lineage V Lassa virus glycoprotein complex (strain Soromba-R)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Glycoprotein GP1	polymer	259	29225.6	3	UniProt (V9VG48) Pfam (PF00798) In PDB	Lassa mammarenavirus
2	a, b, c	Glycoprotein GP2	polymer	406	44692.9	3	UniProt (V9VG48) Pfam (PF00798) Pfam (PF01081) UniProt (by SIFTS) (Q9WXS1) In PDB	Lassa mammarenavirus	Pre-GP-C
3	Z, D, G, J, L...	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	9	In PDB GlyTouCan (G22768VO)
4	Y, E, F, I, M...	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	9	In PDB GlyTouCan (G42666HT)
5	X, H, P	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	3	In PDB GlyTouCan (G21290RB)
6	d, K, S	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	3	In PDB GlyTouCan (G15407YE)
7	A, a, B, b, C...	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	9	Chemie (NAG)

Sequence modifications

A, B, C: 1 - 259 (UniProt: V9VG48)

PDB	External Database	Details
Cys 207	His 242	engineered mutation
Arg 258	Leu 293	engineered mutation
Arg 259	Leu 294	engineered mutation

a, b, c: 260 - 424 (UniProt: V9VG48)

PDB	External Database	Details
Pro 329	Glu 364	engineered mutation
Cys 360	Gly 395	engineered mutation

a, b, c: 425 - 665 (PDB: 8EJF)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	221755.5
Branched	Number of molecules	24
	Total formula weight	15488.3
Non-Polymers*	Number of molecules	9
	Total formula weight	1990.9
All*	Total formula weight	239234.6

*Water molecules are not included.