8EJF
Structure of lineage V Lassa virus glycoprotein complex (strain Soromba-R)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, B, C) | Glycoprotein GP1 | polymer | 259 | 29225.6 | 3 | UniProt (V9VG48) Pfam (PF00798) | Lassa mammarenavirus | |
| 2 | B, D, F (a, b, c) | Glycoprotein GP2 | polymer | 406 | 44692.9 | 3 | UniProt (V9VG48) Pfam (PF00798) Pfam (PF01081) UniProt (by SIFTS) (Q9WXS1) | Lassa mammarenavirus | Pre-GP-C |
| 3 | CA, G, J, M, O... (Z, D, G, J, L...) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 9 | In PDB GlyTouCan (G22768VO) | |||
| 4 | BA, H, I, L, P... (Y, E, F, I, M...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 5 | AA, K, S (X, H, P) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 3 | In PDB GlyTouCan (G21290RB) | |||
| 6 | DA, N, V (d, K, S) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 7 | EA, FA, GA, HA, IA... (A, a, B, b, C...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 259 (UniProt: V9VG48)
a, b, c: 260 - 424 (UniProt: V9VG48)
a, b, c: 425 - 665 (PDB: 8EJF)
| PDB | External Database | Details |
|---|---|---|
| Cys 207 | His 242 | engineered mutation |
| Arg 258 | Leu 293 | engineered mutation |
| Arg 259 | Leu 294 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Pro 329 | Glu 364 | engineered mutation |
| Cys 360 | Gly 395 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 221755.5 | |
| Branched | Number of molecules | 24 |
| Total formula weight | 15488.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1990.9 | |
| All* | Total formula weight | 239234.6 |
