8EJE
Structure of lineage II Lassa virus glycoprotein complex (strain NIG08-A41)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Glycoprotein GP1 | polymer | 254 | 28398.7 | 3 | UniProt (E9K9S8) Pfam (PF00798) In PDB | Lassa mammarenavirus | |
| 2 | a, b, c | Glycoprotein GP2 | polymer | 165 | 19179.8 | 3 | UniProt (E9K9S8) Pfam (PF00798) In PDB | Lassa mammarenavirus | |
| 3 | D, K, R | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 4 | X, E, F, G, H... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 15 | In PDB GlyTouCan (G42666HT) | |||
| 5 | I, P, W | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 6 | A, a, B, b, C... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 254 (UniProt: E9K9S8)
a, b, c: 259 - 423 (UniProt: E9K9S8)
| PDB | External Database | Details |
|---|---|---|
| Cys 206 | Lys 206 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Pro 328 | Glu 328 | engineered mutation |
| Cys 359 | Gly 359 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 142735.5 | |
| Branched | Number of molecules | 21 |
| Total formula weight | 10858.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2654.5 | |
| All* | Total formula weight | 156248.1 |
