8EIY
Cobalt(II)-substituted S48T Horse Liver Alcohol Dehydrogenase in Complex with NADH and N-Cyclohexylformamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alcohol dehydrogenase E chain | polymer | 377 | 40052.5 | 2 | UniProt (P00327) Pfam (PF08240) Pfam (PF00107) | Equus caballus (horse) | |
| 2 | C, F (A, B) | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) | |||
| 3 | D, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, H (A, B) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 2 | Chemie (NAI) | |||
| 5 | I (B) | CYCLOHEXYLFORMAMIDE | non-polymer | 127.2 | 1 | Chemie (CXF) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 374 (UniProt: P00327)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Thr 48 | Ser 49 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80105.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1706.8 | |
| All* | Total formula weight | 81811.7 |
