8EIT
Structure of FFAR1-Gq complex bound to DHA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | A modified Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 238 | 27638.5 | 1 | Homo sapiens (human) | ||
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 82 | 9137.5 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 4 | D (E) | scFv16 | polymer | 318 | 34930.9 | 1 | Homo sapiens (Human) | ||
| 5 | E (R) | Free fatty acid receptor 1 | polymer | 501 | 54298.8 | 1 | UniProt (P00720) UniProt (O14842) Pfam (PF00959) Pfam (PF00001) | Tequatrovirus T4 | G-protein coupled receptor 40 |
| 6 | F (R) | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID | non-polymer | 328.5 | 1 | Chemie (HXA) PubChem (3144) PubChem (22525340) PubChem (177696452) PubChem (25057321) PubChem (25256724) PubChem (445580) PubChem (45934466) PubChem (57417355) PubChem (59892853) PubChem (5353594) PubChem (5496736) PubChem (6433873) PubChem (88160238) PubChem (88160239) PubChem (90107237) PubChem (9819813) PubChem (73013253) PubChem (92449652) PubChem (11529985) PubChem (13034934) PubChem (13034935) PubChem (13034936) PubChem (13034937) PubChem (13034938) PubChem (13034939) PubChem (95246016) PubChem (96883295) PubChem (92041304) PubChem (99719284) PubChem (99940314) PubChem (101408069) PubChem (122652101) PubChem (122652051) PubChem (122652085) PubChem (117949721) PubChem (117968204) PubChem (118537232) PubChem (118595332) PubChem (122651975) PubChem (122651977) PubChem (122651979) PubChem (122651982) PubChem (122651985) PubChem (122652006) PubChem (122652014) PubChem (122652018) PubChem (122652023) PubChem (122652025) PubChem (122652029) PubChem (122652043) PubChem (122652046) PubChem (122652048) PubChem (122652053) PubChem (122652065) PubChem (122652072) PubChem (122652074) PubChem (122652079) PubChem (122652083) PubChem (122652084) PubChem (122652086) PubChem (122652089) PubChem (122652092) PubChem (122652094) PubChem (122652096) PubChem (122652100) PubChem (122652102) PubChem (122652105) PubChem (124102851) PubChem (124102855) PubChem (124102876) PubChem (124102883) PubChem (124102890) PubChem (132895583) PubChem (151038001) PubChem (164511891) PubChem (169552902) PubChem (170343638) PubChem (172878163) PubChem (175738679) |
Sequence modifications
C: 2 - 71 (UniProt: P59768)
R: -168 - -9 (UniProt: P00720)
R: 2 - 300 (UniProt: O14842)
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | expression tag |
| Gly -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -200 | - | initiating methionine |
| Gly -199 | - | expression tag |
| Lys -198 | - | expression tag |
| Thr -197 | - | expression tag |
| Ile -196 | - | expression tag |
| Ile -195 | - | expression tag |
| Ala -194 | - | expression tag |
| Leu -193 | - | expression tag |
| Ser -192 | - | expression tag |
| Tyr -191 | - | expression tag |
| Ile -190 | - | expression tag |
| Phe -189 | - | expression tag |
| Cys -188 | - | expression tag |
| Leu -187 | - | expression tag |
| Val -186 | - | expression tag |
| Phe -185 | - | expression tag |
| Ala -184 | - | expression tag |
| Asp -183 | - | expression tag |
| Tyr -182 | - | expression tag |
| Lys -181 | - | expression tag |
| Asp -180 | - | expression tag |
| Asp -179 | - | expression tag |
| Asp -178 | - | expression tag |
| Asp -177 | - | expression tag |
| Ala -176 | - | expression tag |
| Glu -175 | - | expression tag |
| Asn -174 | - | expression tag |
| Leu -173 | - | expression tag |
| Tyr -172 | - | expression tag |
| Phe -171 | - | expression tag |
| Gln -170 | - | expression tag |
| Gly -169 | - | expression tag |
| Gly -158 | Arg 12 | conflict |
| Thr -116 | Cys 54 | conflict |
| Ala -73 | Cys 97 | conflict |
| Arg -33 | Ile 137 | conflict |
| Leu -8 | - | linker |
| Glu -7 | - | linker |
| Val -6 | - | linker |
| Leu -5 | - | linker |
| Phe -4 | - | linker |
| Gln -3 | - | linker |
| Gly -2 | - | linker |
| Pro -1 | - | linker |
| Glu 0 | - | linker |
| Phe 1 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 163422.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 328.5 | |
| All* | Total formula weight | 163751.0 |
