8EII
Cryo-EM structure of human DNMT3B homo-tetramer (form II)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | DNA (cytosine-5)-methyltransferase 3B | polymer | 650 | 73654.0 | 4 | UniProt (Q9UBC3) Pfam (PF00855) Pfam (PF17980) Pfam (PF21255) Pfam (PF00145) | Homo sapiens (human) | Dnmt3b,DNA methyltransferase HsaIIIB,DNA MTase HsaIIIB,M.HsaIIIB |
| 2 | E, I (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 3 | F, G, H, J, K... (A, B, C) | ZINC ION | non-polymer | 65.4 | 9 | Chemie (ZN) |
Sequence modifications
A, B, C, D: 206 - 853 (UniProt: Q9UBC3)
| PDB | External Database | Details |
|---|---|---|
| Gly 204 | - | expression tag |
| Ser 205 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 294616.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1357.5 | |
| All* | Total formula weight | 295973.6 |
