8EI8
Crystal structure of the WWP2 HECT domain in complex with H308, a Helicon Polypeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | NEDD4-like E3 ubiquitin-protein ligase WWP2 | polymer | 376 | 44925.4 | 1 | UniProt (O00308) Pfam (PF00632) In PDB | Homo sapiens (human) | Atrophin-1-interacting protein 2,AIP2,HECT-type E3 ubiquitin transferase WWP2,WW domain-containing protein 2 |
| 2 | B | H308 | polymer | 19 | 2073.3 | 1 | synthetic construct | ||
| 3 | A | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 6 | B | N,N'-(1,4-phenylene)diacetamide | non-polymer | 192.2 | 1 | Chemie (WHL) |
Sequence modifications
A: 492 - 865 (UniProt: O00308)
| PDB | External Database | Details |
|---|---|---|
| Gly 490 | - | expression tag |
| Pro 491 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46998.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 722.8 | |
| All* | Total formula weight | 47721.5 |
