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8EHL

Crystal Structure of SARS-CoV-2 Main Protease (Mpro) S144M Mutant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
3C-like proteinase nsp5polymer30633869.71UniProt (P0DTD1)
Pfam (PF05409)
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5
2B
(A)
waterwater18.061Chemie (HOH)
Sequence modifications
A: 1 - 306 (UniProt: P0DTD1)
PDBExternal DatabaseDetails
Met 144Ser 3407engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33869.7
All*Total formula weight33869.7
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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