8EHJ

Crystal Structure of SARS-CoV-2 Main Protease (Mpro) H172Q Mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	3C-like proteinase nsp5	polymer	306	33815.5	2	UniProt (P0DTD1) Pfam (PF05409)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)	3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5
2	C, D (A, B)	water	water		18.0	75	Chemie (HOH)

Sequence modifications

A, B: 1 - 306 (UniProt: P0DTD1)

PDB	External Database	Details
Gln 172	His 3435	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67631.1
All*	Total formula weight	67631.1

*Water molecules are not included.