8EF8
Staphylococcus aureus ClpP Y63W in complex with compound 3471
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | ATP-dependent Clp protease proteolytic subunit | polymer | 203 | 22630.7 | 14 | UniProt (Q2G036) Pfam (PF00574) | Staphylococcus aureus subsp. aureus NCTC 8325 | Endopeptidase Clp |
| 2 | AA, BA, DA, FA, GA... (G, I, K, L, M...) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 14 | Chemie (MPD) | |||
| 3 | CA, EA, HA, JA, LA... (I, K, M, N, S...) | (5S,6S,9aS)-N-[(4-fluorophenyl)methyl]-6-methyl-8-[(naphthalen-1-yl)methyl]-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide | non-polymer | 474.5 | 12 | Chemie (USU) | |||
| 4 | AB, BB, OA, PA, QA... (S, T, A, B, C...) | water | water | 18.0 | 968 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, I, K, L, M, N, S, T: 1 - 195 (UniProt: Q2G036)
| PDB | External Database | Details |
|---|---|---|
| Trp 63 | Tyr 63 | engineered mutation |
| Leu 196 | - | expression tag |
| Glu 197 | - | expression tag |
| His 198 | - | expression tag |
| His 199 | - | expression tag |
| His 200 | - | expression tag |
| His 201 | - | expression tag |
| His 202 | - | expression tag |
| His 203 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 316830.1 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 7348.8 | |
| All* | Total formula weight | 324178.9 |
