8EDG
Cryo-EM structure of the Hermes transposase bound to two left-ends of its DNA transposon
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | M, P | DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3') | polymer | 7 | 2162.4 | 2 | Musca domestica | ||
| 2 | N, Q | DNA (46-MER) | polymer | 46 | 14173.1 | 2 | Musca domestica | ||
| 3 | O, R | DNA (55-MER) | polymer | 55 | 16931.9 | 2 | Musca domestica | ||
| 4 | A, C, I, E, G... | Hermes transposase | polymer | 612 | 70210.6 | 6 | UniProt (Q25438) Pfam (PF10683) Pfam (PF05699) In PDB | Musca domestica (house fly) | |
| 5 | A, C, I, E, G... | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) |
Sequence modifications
A, C, I, E, G, K: 1 - 612 (UniProt: Q25438)
| PDB | External Database | Details |
|---|---|---|
| Glu 2 | Gln 2 | engineered mutation |
| Gly 128 | Lys 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 487798.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 392.5 | |
| All* | Total formula weight | 488190.8 |
