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8ED9

cryo-EM structure of TRPM3 ion channel in the presence with PIP2 and PregS, state 2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DTransient receptor potential cation channel, subfamily M, member 3polymer1343154649.34UniProt (Q5F4S7)
Pfam (PF18139)
Pfam (PF00520)
Pfam (PF16519)
In PDB
Mus musculus (house mouse)
2E, F, G, HUnidentified segment at the N-terminus of TRPM3polymer171464.84Mus musculus
3A, B, C, D1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATEnon-polymer705.04Chemie (3PH)
4A, B, C, D(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-ennon-polymer544.84Chemie (9Z9)
5A, B, C, D[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoatenon-polymer746.64Chemie (PIO)
6BSODIUM IONnon-polymer23.01Chemie (NA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight624456.5
Non-Polymers*Number of molecules13
Total formula weight8008.5
All*Total formula weight632465.0
*Water molecules are not included.

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